2026年度

Morishita Y, Takamura Y, Nishimura K, Yokoi Y, Ishihama Y, Idutsu R, Ono M, Matsumoto R, Hitora-Imamura N, Minami M, Nomura H
Infraslow histaminergic dynamics govern priming states to gate moment-to-moment memory accessibility
Neuron. 2026 Jun 11:S0896-6273(26)00411-3. (2026)
DOI: 10.1016/j.neuron.2026.05.019.
https://www.cell.com/neuron/fulltext/S0896-6273(26)00411-3
https://pubmed.ncbi.nlm.nih.gov/42276055/

Suzuki T, Tatsukawa T, Sudo G, Miyamoto H, Zhang Y, Holtzman MJ, Itohara S, Shimohata A, Amano K, Inoue I, Mazaki E & Yamakawa K.
Myoclonin1 haploinsufficiency in motile ciliated cells partially recapitulates epileptic features of Efhc1-deficient mice in adult age
Molecular and Cellular Neuroscience, 2026 Jun:137: 104095. (2026)
DOI: 10.1016/j.mcn.2026.104095.
https://pubmed.ncbi.nlm.nih.gov/42000019/
https://www.sciencedirect.com/science/article/abs/pii/S1044743126000254

Shimada IS, Goto A, Hashimoto Y, Inoue H, Sugawara T, Doura T, Fujita T, Iwata T, Shimmoto R, Takase H, Itoh M, Kiyonaka S & Kato Y.
Light- and chemical-induced ciliary signaling governs dorsal/ventral regionalization of human telencephalic organoids
Nature Communications, 2026 May 22 (2026)
DOI: 10.1038/s41467-026-73505-2
https://pubmed.ncbi.nlm.nih.gov/42173885/
https://www.nature.com/articles/s41467-026-73505-2

Yamagata T, Mizukami H, Hibi Y, Yamakawa K, Suzuki T.
Reduction of Nav1.1 in the dorsal striatum preferentially increases hyperthermia-induced generalized seizures compared with the neocortex and nucleus accumbens
bioRxiv, 2026. 
DOI: 10.64898/2026.05.11.724427. published 14 May 2026.
https://www.biorxiv.org/content/10.64898/2026.05.11.724427v1

Kojima D, Sawada M, Ishimaru T, Ito N, Tateyama S, Adachi K, Kawaguchi H, Satake N, Herranz-Pérez V, García-Verdugo JM, Hirose Y, Ohno N, Kaneko N, Sawamoto K.
Cytoarchitecture of neurogenic niche and neuroblast clusters in the postnatal microminipig brain
Stem Cell Reports. 2026 May 12;21(5):102893.
DOI:10.1016/j.stemcr.2026.102893.
https://www.sciencedirect.com/science/article/pii/S2213671126001049

Uenishi R, Kawata R, Manabe T, Matsuba Y, Mihira N, Takeo T, Saido TC, Hijioka M, Saito T.
CXCL10 drives female-specific tau pathology progression and defines sex-dependent vulnerability in tauopathy model mice
bioRxiv, (2026)
DOI: 10.64898/2026.04.19.719088. published 22 Apr 2026. 
https://www.biorxiv.org/content/10.64898/2026.04.19.719088v1

Suzuki T, Tominaga S, Yokoi Y, Mizukami H, Kobayashi K, Nishida W, Yamashita K, Kondo T, Hibi Y, Yamagata T, Itohara S, Nomura H, Hida H & Yamakawa K.
Reduced cortico-accumbal excitatory input due to Nav1.2 haploinsufficiency impairs sociability independently of dopamine
bioRxiv, (2026)
DOI: 10.64898/2026.04.15.718826. published 16 Apr 2026.
https://www.biorxiv.org/content/10.64898/2026.04.15.718826v1

2025年度

Suzuki T, Kondo T, Yamagata, T, Hibi Y, Mizukami H, Kobayashi K, Yamakawa K.
Reduced activity of nucleus accumbens parvalbumin-expressing fast-spiking inhibitory neurons causes convulsive seizures.
bioRxiv, 2026.
DOI: 10.64898/2026.03.09.710428
published 10 Mar 2026.
https://www.biorxiv.org/content/10.64898/2026.03.09.710428v1

Yamagata T, Suzuki T, Yamakawa K.
Parallel analysis of voltage-gated sodium channel subunits reveals preferential colocalizations of beta-1/Nav1.1 and beta-2/Nav1.2.
bioRxiv, 2026.
DOI: 10.64898/2026.03.12.711489
published 16 Mar 2026.
https://www.biorxiv.org/content/10.64898/2026.03.12.711489v1

Nakamura S, Nakamura Y, Jinnou H, Nakao Y, Yinmon H, Mitsuie T, Koyano K, Ueno M, Miki T, Sawamoto K, Saitoh S, Kusaka T.
Hydrogen gas promotes neuroprotection and upregulates ATF5 expression in neonatal hypoxic-ischemic brain injury
Exp Neurol, 2026 Mar:397: 115590. (2026)
DOI: 10.1016/j.expneurol.2025.115590
https://pubmed.ncbi.nlm.nih.gov/41386344/
https://www.sciencedirect.com/science/article/abs/pii/S0014488625004558?via%3Dihub

Hirose I, Hanamatsu H, Mizumoto S, Yamashita R, Yamada S, Furukawa J, Furuichi T and Yagi H.
Structural Characterization of Glycoprotein Glycans and Glycosaminoglycans of Brain Tissues in Slc35a3-Knockout Mice
Int Mol Sci, 2026 Feb 8;27(4), 1643. (2026)
DOI: 10.3390/ijms27041643
https://www.mdpi.com/1422-0067/27/4/1643
https://pubmed.ncbi.nlm.nih.gov/41751780/

Yamada S, Okada K, Ito H, Iseki C, Yamanaka T, Tanikawa M, Otani T, Ii S, Watanabe Y, Wada S, Oshima M, Mase M.
Interthalamic Adhesion as a Potential Structural Regulator of Cerebrospinal Fluid Dynamics in the Third Ventricle
Aging Dis, 2025 Dec 10. (2025)
DOI: 10.14336/AD.2025.1352.
https://www.aginganddisease.org/EN/10.14336/AD.2025.1352
https://pubmed.ncbi.nlm.nih.gov/41400578/

Manabe T, Saito T.
A decade progress in the phenotyping of AppNL-G-F knock-in mouse model of Alzheimer’s disease.
Neuroscience Research. 220: 104959 (2025)
DOI: 10.1016/j.neures.2025.104959
published Nov 2025.（総説）
https://www.sciencedirect.com/science/article/pii/S0168010225001427
https://pubmed.ncbi.nlm.nih.gov/40998178/

Kuboyama K, Muraoka T, and Sawamoto K.
From pathways to platforms: Scaffold-basedstrategies to promote neuronal migration in brain repair
Cell Biomaterials, 100245 (2025)
DOI: 10.1016/j.celbio.2025.100245
published 28 Oct 2025.（総説）
https://www.cell.com/cell-biomaterials/fulltext/S3050-5623(25)00236-3?utm_medium=homepage

Ogino T, Saito A, Sawada M, Takemura S, Hara Y, Yoshimura K, Nagase J, Kawase H, Sato T, Inada H, Herranz-Pérez V, Mukouyama Y, Ema M, García-Verdugo JM, Nabekura J, Sawamoto K.
Neuronal migration depends on blood flow in the adult mammalian brain
eLife, 2025 Oct 28:13:RP99502. (2025)
DOI: 10.7554/eLife.99502.3
https://pubmed.ncbi.nlm.nih.gov/41146614/
https://elifesciences.org/articles/99502

Akter S, Mirhosseiniardakani S, Takekoshi Y, Qiu L, Baker K, Jiang K, Lyon M, Hattori M, and Chen X.
Reelin Controls the Directional Orientation, Apical Localization and Length of Primary Cilia in Principal Neurons in the Cerebral Cortex
bioRxiv [Preprint]. 2025 Oct 15:2025.08.24.672028 (2025)
DOI: 10.1101/2025.08.24.672028
published 15 Oct 2025.
https://www.biorxiv.org/content/10.1101/2025.08.24.672028v1
https://pubmed.ncbi.nlm.nih.gov/40894628/

Yamada S, Okada K, Ito H, Fujinami R, Yamanaka T, Yamada H, Tanikawa M, Iseki C, Watanabe Y, Ii S, Otani T, Wada S, Oshima M, Mase M.
Cerebrospinal Fluid Flow and Vorticity in Hydrocephalus on 4-Dimensional Flow MRI
Neurosurgery Pract. 2025 Oct 2;6(4):e000166. (2025)
DOI:10.1227/neuprac.0000000000000166
https://journals.lww.com/neurosurgpraconline/fulltext/2025/12000/cerebrospinal_fluid_flow_and_vorticity_in.8.aspx
https://pubmed.ncbi.nlm.nih.gov/41163735/

Uenishi R,  Kawata R,  Manabe T,  Takeo T, Hijioka M,  Saito T.
Fingolimod treatment exacerbates tau phosphorylation and neurodegeneration in a mouse model of tauopathy with accumulated brain CD8⁺ T cells
Brain Commun. 2025 Sep 25;7(5):fcaf330. (2025)
DOI: 10.1093/braincomms/fcaf330
https://academic.oup.com/braincomms/article/7/5/fcaf330/8262117
https://pubmed.ncbi.nlm.nih.gov/41000171/

Takekoshi Y, Ando H, Kohno T, Takase H, TTaguchi T, Arita M, Kobayashi T, Hattori M.
Reelin Increases the Sphingomyelin Content of the Plasma Membrane and Affects the Surface Expression of GPI-Anchored Proteins in Hippocampal Neurons
J Neurochem, 2025 Sep;169(9):e70225. (2025)
DOI: 10.1111/jnc.70225.
https://onlinelibrary.wiley.com/doi/10.1111/jnc.70225
https://pubmed.ncbi.nlm.nih.gov/40899734/

Takemura S, Kawase K, Wolbeck L, Nakamura Y, Matsumoto M, Jinnou H, Tahara A, Sawada M, Kubota Y, Herranz-Pérez V, García-Verdugo JM, Ishibashi N, Gallo V, Ohno N, Khodosevich K, Sawamoto K.
Transformation of radial glia into postnatal neural stem cells depends on birth.
Cell Reports, 2025 Aug 26;44(8):116029. (2025)
DOI: 10.1016/j.celrep.2025.116029.
https://www.sciencedirect.com/science/article/pii/S2211124725008009?via%3Dihub
https://pubmed.ncbi.nlm.nih.gov/40713958/　

Furutani N, Murata Y, Miwa W, Nakamura M, Nakajima-Ohyama K C.
Individual and environmental risk factors for post-traumatic stress among hospital nurses after the 2024 Noto Peninsula earthquake in Japan
Front Psychiatry, 2025 Aug 25:16:1631694. (2025)
DOI: 10.3389/fpsyt.2025.1631694.
https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2025.1631694/full
https://pubmed.ncbi.nlm.nih.gov/40927015/

Kanzawa T, Nakajima C, Sawada M, Sawamoto K.
How Growth Cones Sense Extracellular Cues and Drive Neuronal Migration.
BioEssays, 2025 Oct; 47(10):e70050 (2025)
DOI: 10.1002/bies.70050.
published online 15 Aug 2025.　（総説）
https://onlinelibrary.wiley.com/doi/full/10.1002/bies.70050
https://pubmed.ncbi.nlm.nih.gov/40817633/

Suzuki T, Aguan K, Mizuno H, Inoue I, Mikoshiba K, Miyawaki A, Yamakawa K.
Epilepsy protein myoclonin1 interacts with inositol 1,4,5-trisphosphate receptor and reduces calcium ions stored in endoplasmic reticulum.
Explor Neurosci, 2025,4: 100699. (2025)
DOI: 10.37349/en.2025.100699 published 09 July 2025.
https://www.explorationpub.com/Journals/en/Article/100699

Torrijos-Saiz LI, Freixes J, Desfilis E, Medina L, Sawamoto K, García-Verdugo JM, Herranz-Pérez V.
Cellular Organization and Migration Pathways of the Ventricular-Subventricular Zone in the Juvenile Swine Brain (Sus scrofa domesticus)
J Comp Neurol, 2025 Jul;533(7): e70070 (2025)
DOI: 10.1002/cne.70070.
https://onlinelibrary.wiley.com/doi/10.1002/cne.70070
https://pubmed.ncbi.nlm.nih.gov/40605129/　

Ishida S, Yamada S, Oki T, Otani T, Hiratsuka S, Wada S, Mitsuhito Mase M, Watanabe Y.
Evaluation of Interstitial Fluid Volume and Diffusivity in Patients With Idiopathic Normal Pressure Hydrocephalus Using Spectral Diffusion Analysis
Journal of Magnetic Resonance Imaging, 2025 Oct; 62(4): 1092-1104 (2025)
DOI: 10.1002/jmri.29834
https://pubmed.ncbi.nlm.nih.gov/40614019/

Wang W, Kumegawa K, Chapman OS, Shiraishi R, Xiao Z, Okonechnikov K, YSun Y, Pfister SM, Feng W, Uesaka N, Hoshino M, Takahashi S, Korshunov A, Chavez L, Maruyama R, Kawauchi D.
Chromatin Modification Abnormalities by CHD7 and KMT2C Loss Promote Medulloblastoma Progression.
Cell Reports, 2025 May 27;44(5):115673. (2025)
DOI: 10.1016/j.celrep.2025.115673
https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00444-9
https://pubmed.ncbi.nlm.nih.gov/40393452/

2024年度

Sawada M, Nakajima C, Umeda E, Takagi Y, Nakashima N, Vepřek NA, Küllmer F, Nasufović V, Arndt HD, Trauner D, Igarashi M & Sawamoto K.
Time-Lapse Super-Resolution Imaging and Optical Manipulation of Growth Cones in Elongating Axons and Migrating Neurons.
Bio-protocol, 2025 Mar 20;15(6): e5251. (2025)
DOI: 10.21769/BioProtoc.5251.
https://bio-protocol.org/en/bpdetail?id=5251&type=0
https://pubmed.ncbi.nlm.nih.gov/40395842/

Yamada S,  Yuzawa T,  Ito H,  Iseki C, Kondo T,  Yamanaka T,  Tanikawa M, Otani T,  Ii S,  Ohta Y, Watanabe Y, Wada S,  Oshima M,  Mase M.
Regional brain volume changes in Hakim’s disease versus Alzheimer’s and mild cognitive impairment 
Brain Commun. 2025 Mar  26;7(2):fcaf122. (2025)
DOI: 10.1093/braincomms/fcaf122
https://academic.oup.com/braincomms/article/7/2/fcaf122/8093450
https://pubmed.ncbi.nlm.nih.gov/40235958/

Jinnou H, Rosko LM, Yamashita S, Henmi S, Prasad J, Lam VK, Agaronyan A, Tu TW, Imamura Y, Kuboyama K, Sawamoto K, Hashimoto-Torii K, Ishibashi N, Gallo V.
Outer radial glia (neural stem cells in the human neonatal brain) promotes white matter regeneration. 
Cell Reports Medicine. 2025 Mar 18;6(3):101986 (2025)
DOI: 10.1016/j.xcrm.2025.101986.
https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00059-X
https://pubmed.ncbi.nlm.nih.gov/40023165/

Mitsuharu Hattori M.
Regulatory mechanism of Reelin activity: a platform for exploiting Reelin as a therapeutic agent
Front Mol Neurosci, 18: 1546083 (2025)
DOI: 10.3389/fnmol.2025.1546083
published Jan 27 2025.（総説）
https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2025.1546083/full
https://pubmed.ncbi.nlm.nih.gov/39931643/

Kawase K, Nakamura Y, Wolbeck L, Takemura S, Zaitsu K, Ando T, Jinnou H, Sawada M, Nakajima C, Rydbirk R, Gokenya S, Ito A, Fujiyama H, Saito A, Iguchi A, Kratimenos P, Ishibashi N, Gallo V, Iwata O, Saitoh S, Khodosevich K, Sawamoto K. 
Significance of birth in the maintenance of quiescent neural stem cells. 
Sci Adv. Jan 24;11(4):eadn6377 (2025)
DOI: 10.1126/sciadv.adn6377
https://www.science.org/doi/10.1126/sciadv.adn6377
https://pubmed.ncbi.nlm.nih.gov/39841848/

Miyamoto T, Kuboyama K, Honda M, Ohkawa Y, Oki S, Sawamoto K. 
High spatial resolution gene expression profiling and characterization of neuroblasts migrating in the peri-injured cortex using photo-isolation chemistry. 
Front Neurosci. 2025 Jan 7:18:1504047  (2025)
DOI:10.3389/fnins.2024.1504047
https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2024.1504047/full
https://pubmed.ncbi.nlm.nih.gov/39840011/